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View Structure Prediction Details

Protein: gi|2656143, gi|1...
Organism: Homo sapiens
Length: 916 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2656143, gi|1....

Description E-value Query
Range
Subject
Range
gi|62897009 - gi|62897009|dbj|BAD96445.1| ubiquitin specific protease, proto-oncogene isoform b variant [Homo sapi...
0.0 [1..916] [1..916]
gi|114586840 - gi|114586840|ref|XP_001163407.1| PREDICTED: ubiquitin specific protease, proto-oncogene isoform 7 [P...
0.0 [1..916] [1..915]
gi|73985807 - gi|73985807|ref|XP_533829.2| PREDICTED: similar to ubiquitin specific protease, proto-oncogene isofo...
0.0 [1..916] [74..1037]
gi|15030172 - gi|15030172|gb|AAH11341.1| Usp4 protein [Mus musculus]
0.0 [1..916] [1..915]
gi|34932905, gi|... - ref|XP_214377.2| similar to Usp4 protein [Rattus norvegicus], gi|157824037|ref|NP_001099563.1| ubiqu...
0.0 [1..916] [1..914]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEGGGCRER PDAETQKSEL GPLMRTTLQR GAQWYLIDSR WFKQWKKYVG FDSWDMYNVG  60
   61 EHNLFPGPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1w6vA
Description: Solution structure of the DUSP domain of hUSP15
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.69173405245576 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.43109370848144 bayes_pls_golite062009
endopeptidase activity 2.75397594334424 bayes_pls_golite062009
hydrolase activity 2.73447072772242 bayes_pls_golite062009
binding 2.43973746940455 bayes_pls_golite062009
cysteine-type peptidase activity 2.03076448806511 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.33423779714503 bayes_pls_golite062009
protein binding 1.14776614585261 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.95030254676609 bayes_pls_golite062009
ubiquitin-specific protease activity 0.72977635292048 bayes_pls_golite062009
catalytic activity 0.639120026974844 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [70-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNSGLFSDPE SQTLKEHLID ELDYVLVPTE AWNKLLNWYG CVEGQQPIVR KVVEHGLFVK  60
   61 HCKVEVYLLE LKLCENSDPT NVLSCHFSKA DTIATIEKEM RKLFNIPAER ETRLWNKYMS 120
  121 NTYEQLSKLD NTVQDAGLYQ GQVLVIEPQN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.154902
Match: 2g43A
Description: No description for 2g43A was found.

Predicted Domain #3
Region A:
Residues: [220-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDGTWPRQTL QSNGSGFSAS YNCQEPPSSH IQPGLCGLGN LGNTCFMNSA LQCLSNTAPL  60
   61 TDYFLKDEYE AEINRDNPLG MKGEIAEAYA ELIKQMWSGR DAHVAPRMFK TQVGRFAPQF 120
  121 SGYQQQDSQE LLAFLLDGLH EDLNRVKKKP YLELKDANGR PDAVVAKEAW ENHRLRNDSV 180
  181 IVDTFHGLFK STLVCPECAK VSVTFDPFCY LTLPLPLKKD RVMEVFLVPA DPHCRPTQYR 240
  241 VTVPLMGAVS DLCEALSRLS GIAAENMVVA DVYNHRFHKI FQMDEGLNHI MPRDDIFVYE 300
  301 VCSTSVDGSE CVTLPVYFRE RKSRPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.09691
Match: 2gfoA
Description: No description for 2gfoA was found.

Predicted Domain #4
Region A:
Residues: [546-916]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSSASALYG QPLLLSVPKH KLTLESLYQA VCDRISRYVK QPLPDEFGSS PLEPGACNGS  60
   61 RNSCEGEDEE EMEHQEEGKE QLSETEGSGE DEPGNDPSET TQKKIKGQPC PKRLFTFSLV 120
  121 NSYGTADINS LAADGKLLKL NSRSTLAMDW DSETRRLYYD EQESEAYEKH VSMLQPQKKK 180
  181 KTTVALRDCI ELFTTMETLG EHDPWYCPNC KKHQQATKKF DLWSLPKILV VHLKRFSYNR 240
  241 YWRDKLDTVV EFPIRGLNMS EFVCNLSARP YVYDLIAVSN HYGAMGVGHY TAYAKNKLNG 300
  301 KWYYFDDSNV SLASEDQIVT KAAYVLFYQR RDDEFYKTPS LSSSGSSDGG TRPSSSQQGF 360
  361 GDDEACSMDT N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.522879
Match: 2hd5A
Description: No description for 2hd5A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle