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Protein Overview: RNPH_PSEA8

General Information:
Name(s) found: RNPH_PSEA8 [Swiss-Prot]
Description(s) found:
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  • gi|226736925|sp|B7V5M5.1|RNPH_PSEA8 RecName: Full=Ribonuclease PH; Short=RNase PH; AltName: Full=tRNA nucleotidyltransferase [NCBI NR]
  • gi|218894437|ref|YP_002443307.1| ribonuclease PH [Pseudomonas aeruginosa LESB58] [NCBI NR]
  • gi|218774666|emb|CAW30483.1| ribonuclease PH [Pseudomonas aeruginosa LESB58] [NCBI NR]
  • Ribonuclease PH OS=Pseudomonas aeruginosa (strain LESB58) GN=rph PE=3 SV=1 [Swiss-Prot]
    • Organism: Pseudomonas aeruginosa LESB58
    Length: 239 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRPSGRAAD QLRPIRITRH YTKHAEGSVL VEFGDTKVIC TVSAESGVPR FLKGQGQGWL  60
   61 TAEYGMLPRS TGERNQREAS RGKQGGRTLE IQRLIGRSLR AALDLSKLGE NTLYIDCDVI 120
  121 QADGGTRTAS ITGATVALID ALAVLKKRGA LKGNPLKQMV AAVSVGIYQG VPVLDLDYLE 180
  181 DSAAETDLNV VMTDAGGFIE VQGTAEGAPF RPAELNAMLE LAQQGMQELF ELQRAALAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..239] PSI-BLAST 77.154902 Crystal Structure Of The tRNA Processing Enzyme Rnase pH From Pseudomonas Aeruginosa

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • exoribonuclease activity
    		•  7.55877202113513 bayes_pls_golite062009
  • ribonuclease activity
    		•  7.54644729272203 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  7.5310318714913 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  6.46930372693262 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  4.29895100594643 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  3.83939403332553 bayes_pls_golite062009
  • exonuclease activity
    		•  3.40686901061667 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.86434572018929 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.90115575554186 bayes_pls_golite062009
  • structural molecule activity
    		•  1.69321127364043 bayes_pls_golite062009
  • hydrolase activity
    		•  1.55476709794855 bayes_pls_golite062009
  • RNA binding
    		•  1.36549953164096 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20748032530392 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.05662964529454 bayes_pls_golite062009
  • binding
    		•  0.907487229190259 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • DNA binding
    		•  0.828609700556836 bayes_pls_golite062009
  • nuclease activity
    		•  0.69721312877891 bayes_pls_golite062009
  • tRNA-specific ribonuclease activity
    		•  0.383567539949931 bayes_pls_golite062009
  • mRNA binding
    		•  0.17546516359584 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.1173709890655 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle