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Protein Overview: gi|162318152, gi...

General Information:
Name(s) found: gi|162318448 [NCBI NR]
gi|162318152 [NCBI NR]
Description(s) found:
Found 2 descriptions.
SHOW ALL
  • gi|162318448|gb|AAI56048.1| Amyloid beta (A4) precursor protein-binding, family A, member 1 [synthetic construct] [NCBI NR]
  • gi|162318152|gb|AAI57031.1| Amyloid beta (A4) precursor protein-binding, family A, member 1 [synthetic construct] [NCBI NR]
    • Organism: synthetic construct
    Length: 837 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHLEGSAEV EVTDEAAGGE VNESVEADLE HPEVEEEQQQ PPQQQHYVGR HQRGRALEDL  60
   61 RAQLGQEEEE RGECLARSAS TESGFHNHTD TAEGDVIAAA RDGYDAERAQ DPEDESAYAV 120
  121 QYRPEAEEYT EQAEAEHAEA THRRALPNHL HFHSLEHEEA MNAAYSGYVY THRLFHRGED 180
  181 EPYSEPYADY GGLQEHVYEE IGDAPELDAR DGLRLYEQER DEAAAYRQEA LGARLHHYDE 240
  241 RSDGESDSPE KEAEFAPYPR MDSYEQEEDI DQIVAEVKQS MSSQSLDKAA EDMPEAEQDL 300
  301 ERPPTPAGGR PDSPGLQAPA GQQRAVGPAG GGEAGQRYSK EKRDAISLAI KDIKEAIEEV 360
  361 KTRTIRSPYT PDEPKEPIWV MRQDISPTRD CDDQRPMDGD SPSPGSSSPL GAESSSTSLH 420
  421 PSDPVEASTN KESRKSLASF PTYVEVPGPC DPEDLIDGII FAANYLGSTQ LLSDKTPSKN 480
  481 VRMMQAQEAV SRIKMAQKLA KSRKKAPEGE SQPMTEVDLF ISTQRIKVLN ADTQETMMDH 540
  541 PLRTISYIAD IGNIVVLMAR RRMPRSNSQE NVEASHPSQD GKRQYKMICH VFESEDAQLI 600
  601 AQSIGQAFSV AYQEFLRANG INPEDLSQKE YSDLLNTQDM YNDDLIHFSK SENCKDVFIE 660
  661 KQKGEILGVV IVESGWGSIL PTVIIANMMH GGPAEKSGKL NIGDQIMSIN GTSLVGLPLS 720
  721 TCQSIIKGLK NQSRVKLNIV RCPPVTTVLI RRPDLRYQLG FSVQNGIICS LMRGGIAERG 780
  781 GVRVGHRIIE INGQSVVATP HEKIVHILSN AVGEIHMKTM PAAMYRLLTA QEQPVYI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] MSA 1.233992 View MSA. No confident structure predictions are available.
    2 View Details [172..254] deduced N/A No confident structure predictions are available.
    3 View Details [255..419] MSA 3.251996 View MSA. No confident structure predictions are available.
    4 View Details [420..504] FFAS03 0.96 Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
    5 View Details [505..757] PSI-BLAST 7.221849 Structural analysis of DegS, a stress sensor of the bacterial periplasm
    6 View Details [758..837] PSI-BLAST 64.39794 Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  3.30438399835377 bayes_pls_golite062009
  • protein binding
    		•  1.85780451223644 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.33652392843319 bayes_pls_golite062009
  • signal transducer activity
    		•  1.33652392843319 bayes_pls_golite062009
  • transporter activity
    		•  1.29925758003665 bayes_pls_golite062009
  • clathrin binding
    		•  1.26358983594552 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.18949469885023 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07608551024196 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.907985718286156 bayes_pls_golite062009
  • phospholipid binding
    		•  0.864843473490307 bayes_pls_golite062009
  • DNA binding
    		•  0.818468074940498 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.650240628628722 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.552872712432362 bayes_pls_golite062009
  • phosphoinositide binding
    		•  0.45899353522401 bayes_pls_golite062009
  • receptor binding
    		•  0.391425518916624 bayes_pls_golite062009
  • receptor activity
    		•  0.257794982570723 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.102504792589299 bayes_pls_golite062009
    5
    Term Confidence Notes
  • hydrolase activity
    		•  2.11987336027745 bayes_pls_golite062009
  • peptidase activity
    		•  2.03396925424902 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.75197091966116 bayes_pls_golite062009
  • endopeptidase activity
    		•  1.63841663816937 bayes_pls_golite062009
  • binding
    		•  1.4493073430417 bayes_pls_golite062009
  • PDZ domain binding
    		•  1.4161955255054 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • transporter activity
    		•  1.18978519116375 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.14575507779171 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.10854960463642 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07211582292329 bayes_pls_golite062009
  • DNA binding
    		•  0.959755415594752 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  0.766679710300835 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.757825908093539 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.743422247748155 bayes_pls_golite062009
  • signal transducer activity
    		•  0.702950445770193 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.702950445770193 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.500408526353621 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  0.486187854727418 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  0.449763185979101 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.304039235146353 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252733105474942 bayes_pls_golite062009
  • receptor activity
    		•  0.180964966947445 bayes_pls_golite062009
  • protein binding
    		•  0.153868222781357 bayes_pls_golite062009
  • cystic fibrosis transmembrane conductance regulator binding
    		•  0.114699700156051 bayes_pls_golite062009
  • syntaxin-6 binding
    		•  0.114699700156051 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0187659836234897 bayes_pls_golite062009
    6
    Term Confidence Notes
  • binding
    		•  3.40143803981618 bayes_pls_golite062009
  • protein binding
    		•  2.25893018754605 bayes_pls_golite062009
  • PDZ domain binding
    		•  1.4161955255054 bayes_pls_golite062009
  • transporter activity
    		•  1.18978519116375 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.10854960463642 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07211582292329 bayes_pls_golite062009
  • signal transducer activity
    		•  0.877891218909175 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.877891218909175 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  0.766679710300835 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.500408526353621 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  0.449763185979101 bayes_pls_golite062009
  • receptor binding
    		•  0.359972518335054 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.304039235146353 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252733105474942 bayes_pls_golite062009
  • cystic fibrosis transmembrane conductance regulator binding
    		•  0.114699700156051 bayes_pls_golite062009
  • syntaxin-6 binding
    		•  0.114699700156051 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0187659836234897 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle