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Protein Overview: GET2

General Information:
Name(s) found: GET2 / YER083C [SGD]
Description(s) found:
Found 12 descriptions.
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  • Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for meiotic nuclear division [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 307 amino acids

    Gene Ontology:
    Cellular Component: GET complex [IGILink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: retrograde vesicle-mediated transport, Golgi to ER [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    cellular cell wall organization [IEPLink to PubMed article][IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIWICTNELF HVCSISNVAL GNMSELTEAE KRRLLRERRQ KKFSNGGASS RLNKITGQAS  60
   61 SHLNAESPLD APSAAKTTPP ASVHSATPDI KEDSNVAPQL DLLKQLAAMQ GQGTGKSTPQ 120
  121 DSSTPDLLSL LSSMNTGMPS AEGTPSFGQA APAAPINQAA LDYHDYLLNR LKAWTILVKW 180
  181 VFFLLPYLYL ITRPNSSVWP AYAFTQSAWF APLRNPSNFT RIFATFEFLS ISIYYQLLKN 240
  241 VEHKSKIKNL QDTNKLVKLV SLVPEGVIPV ANLKGKLITL LQYWDLLSML ITDISFVLIV 300
  301 LGLLTYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..307] ORFEUS 7.05 Alpha subunit of glutamate synthase, C-terminal domain; Alpha subunit of glutamate synthase, central and FMN domains; Alpha subunit of glutamate synthase, N-terminal domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle