YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: YEH1

General Information:
Name(s) found: YEH1 / YLL012W [SGD]
Description(s) found:
Found 28 descriptions.
SHOW ALL
  • Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 573 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDALink to PubMed articleLink to PubMed article]
    integral to membrane [IDALink to PubMed article]
    Biological Process: sterol metabolic process [IMPLink to PubMed article]
    Molecular Function: sterol esterase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVSAVLKRA RNLLATFIVC CFMAVVLVLA LAHHFINEHR DTRSSSTQIE VDDESKRNVH  60
   61 HDHVLTRTNA YATPYLDLEH DKKNGIVYDH TRTVVRKKNH EVGSSSLHKN LFHKFLTKLI 120
  121 FRFIEKEKVT EGVTQGKFNN SSNEIANHEP VFEKIPVQCD NPLQNLILSE DLTLVADLNY 180
  181 YFNQYNIQIE EFRLETEDGF VIDLWHLIPK YRTTDSDKKK RPPILMLHGL LQSSGSFASN 240
  241 GRKSLAYFLY QSGYDIWLGN NRCGFRPEWN EAKVPTLASR WDWDLREMVK YDLTLLIDTV 300
  301 LAKTQFEKLT LISHSQGTTQ GFMGLVNEDK FFPPGSGSKE SFFTSKIANY IALAPAVYPG 360
  361 PLLNEKLFVK LMTKEIENPW FFGETSFFEI MMIVRNLCVG ESLFSFVCYT IFNYLFDWND 420
  421 TLWDTALRDR HFLFSPVHVS VKLMQWWLSP DPNKVSFKFG SHKMFPDNVK WFSDASKAPN 480
  481 IYLFVPKQDR LVDGERLINH FVNVESNVNY KIWYIDEYAH IDVLWAHDVI ERIGKPILQN 540
  541 LNNYYSKKPS SAFESDCSDT EVETELEMVA EKA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ERG7 TGL1 TGL3 TGL4 TGL5 YEH1 YEH2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YEH1 Huh WK, et al. (2003)
    View Data YEH1 and ERG6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] deduced N/A No confident structure predictions are available.
    2 View Details [139..573] PSI-BLAST 307.616428 Gastric lipase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity
    		•  3.20549979663539 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  2.5858992959971 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  1.62335985481548 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • triglyceride lipase activity
    		•  1.2959733599348 bayes_pls_golite062009
  • sterol esterase activity
    		•  1.21262745914703 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  1.18565704009692 bayes_pls_golite062009
  • peptidase activity
    		•  0.858311047004898 bayes_pls_golite062009
  • lipase activity
    		•  0.849473630399459 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.590445773074315 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.459339891351725 bayes_pls_golite062009
  • carboxylesterase activity
    		•  0.424330502936163 bayes_pls_golite062009
  • acyl-CoA thioesterase activity
    		•  0.35429970866093 bayes_pls_golite062009
  • binding
    		•  0.351031277062254 bayes_pls_golite062009
  • receptor binding
    		•  0.101189098492974 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle