Protein Overview: SPS4

General Information:
Name(s) found:	SPS4 / YOR313C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|940844\|emb\|CAA62168.1\| 06120 [Saccharomyces cerevisiae] [NCBI NR] gi\|6324889\|ref\|NP_014958.1\| Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage; Sps4p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S58324 sporulation-specific protein SPS4 - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1711501\|sp\|P09937.2\|SPS4_YEAST RecName: Full=Sporulation-specific protein 4 [NCBI NR] gi\|1420688\|emb\|CAA99633.1\| SPS4 [Saccharomyces cerevisiae] [NCBI NR] Sporulation-specific protein 4 OS=Saccharomyces cerevisiae GN=SPS4 PE=1 SV=2 [Swiss-Prot] SPS4 Sporulation-specific protein [mips] Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage [SGD] (P09937) Sporulation-specific protein 4 [4932.FASTACCERV.txt] Chr XV from 902867-901851, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XV from 901850-902866, reverse complement [yeastorf3.fasta] Chr XV from 901851-902867, reverse complement [yeastorf4.fasta] SPS4, Chr XV from 901850-902866, reverse complement [yeast_orfs2] SPS4 SGDID:S0005840, Chr XV from 902869-901853, reverse complement, Verified ORF [yeastflysequest.fasta] Sps4p [Saccharomyces cerevisiae]gi\|1420688\|emb\|CAA99633.1\| SPS4 [Saccharomyces cerevisiae]gi\|940844\|emb\|CAA62168.1\| 06120 [Saccharomyces cerevisiae]gi\|1711501\|sp\|P09937\|SPS4_YEAST Sporulation-specific protein 4gi\|2133151\|pir\|\|S58324 sporulation-specif [nrdb_11152004_Chlamydomonas] SPS4 SGDID:S000005840, Chr XV from 902869-901853, reverse complement, Verified ORF, "Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] SPS4 SGDID:S000005840, Chr XV from 902871-901855, reverse complement, Verified ORF, "Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage" [yeast-contam.fasta] Sporulation-specific protein 4 [nr-271106-contam.fasta] 06120 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage; Sps4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] SPS4 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Sporulation-specific protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPS4 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SPS4 SGDID:S000005840, Chr XV from 902874-901858, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage" [yeast-030211-contam.fasta] SPS4 SGDID:S000005840, Chr XV from 902874-901858, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage" [20141208_orf_trans.fasta] YOR313C SGDID:S000005840, Chr XV from 902874-901858, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] Sporulation-specific protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPS4 PE=2 SV=2 [uniprot_sprot.fasta.20160308]
Organism:	Saccharomyces cerevisiae
Length:	338 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	ascospore formation [IEP] DNA metabolic process [IGI] meiosis [IEP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSNLNIVKV TKPQEENKNF LHKNTNEPNE MEQSQTQEAV TENFTENSNL SANEHAARRG  60
   61 RLNLKTVDHI ETYPIVQETE EIAKKIALTR IILAQTKPRI DKVVVSRPVQ AVAPVVNFFD 120
  121 KMANSTLSTV ERVVPSLKTK TYKRLGEEIA LPYTLSKKYG KQLRDTTARN GDNYVYQPVH 180
  181 GRLMKFRKYY NEKFIDTKGK PLIRGQLDPV LLPVNNTFEK VTVKYLPKGK KVPNDSFSCE 240
  241 FNRGLALEYN FMTRAVSAVS HQVVGIAKLP IAYGYHTNSV YNKNLDKQAD LKMKNVLRGT 300
  301 WDTITDLERE IWASVTDRSL FRFFGNKSEG GDLPHLVQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#02 Alpha Factor Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MEC3	SPS4	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..338]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2