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Protein Overview: POS5

General Information:
Name(s) found: POS5 / YPL188W [SGD]
Description(s) found:
Found 21 descriptions.
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  • Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 414 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: response to oxidative stress [IMPLink to PubMed article]
    NADP biosynthetic process [IDALink to PubMed article]
    Molecular Function: NADH kinase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVRVKLNKP VKWYRFYSTL DSHSLKLQSG SKFVKIKPVN NLRSSSSADF VSPPNSKLQS  60
   61 LIWQNPLQNV YITKKPWTPS TREAMVEFIT HLHESYPEVN VIVQPDVAEE ISQDFKSPLE 120
  121 NDPNRPHILY TGPEQDIVNR TDLLVTLGGD GTILHGVSMF GNTQVPPVLA FALGTLGFLS 180
  181 PFDFKEHKKV FQEVISSRAK CLHRTRLECH LKKKDSNSSI VTHAMNDIFL HRGNSPHLTN 240
  241 LDIFIDGEFL TRTTADGVAL ATPTGSTAYS LSAGGSIVSP LVPAILMTPI CPRSLSFRPL 300
  301 ILPHSSHIRI KIGSKLNQKP VNSVVKLSVD GIPQQDLDVG DEIYVINEVG TIYIDGTQLP 360
  361 TTRKTENDFN NSKKPKRSGI YCVAKTENDW IRGINELLGF NSSFRLTKRQ TDND

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data POS5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] deduced N/A No confident structure predictions are available.
    2 View Details [98..414] Pfam 109.337242 ATP-NAD kinase No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle