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Protein Overview: MMAA

General Information:
Name(s) found: MMAA [HGNC (HUGO)]
Description(s) found:
Found 28 descriptions.
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  • methylmalonic aciduria (cobalamin deficiency) cblA type [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 418 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPMLLPHPHQ HFLKGLLRAP FRCYHFIFHS STHLGSGIPC AQPFNSLGLH CTKWMLLSDG  60
   61 LKRKLCVQTT LKDHTEGLSD KEQRFVDKLY TGLIQGQRAC LAEAITLVES THSRKKELAQ 120
  121 VLLQKVLLYH REQEQSNKGK PLAFRVGLSG PPGAGKSTFI EYFGKMLTER GHKLSVLAVD 180
  181 PSSCTSGGSL LGDKTRMTEL SRDMNAYIRP SPTRGTLGGV TRTTNEAILL CEGAGYDIIL 240
  241 IETVGVGQSE FAVADMVDMF VLLLPPAGGD ELQGIKRGII EMADLVAVTK SDGDLIVPAR 300
  301 RIQAEYVSAL KLLRKRSQVW KPKVIRISAR SGEGISEMWD KMKDFQDLML ASGELTAKRR 360
  361 KQQKVWMWNL IQESVLEHFR THPTVREQIP LLEQKVLIGA LSPGLAADFL LKAFKSRD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] deduced N/A No confident structure predictions are available.
    2 View Details [85..418] PSI-BLAST 53.154902 No description for 2qm7A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.03298441743645 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.98617097875287 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.96633266544098 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.96437252410847 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.59627719545436 bayes_pls_golite062009
  • transporter activity
    		•  1.5835033929282 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  1.53837763663408 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.53657633349085 bayes_pls_golite062009
  • ATPase activity
    		•  1.44825977402161 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.38807279858296 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.30978934925464 bayes_pls_golite062009
  • binding
    		•  1.29379382725969 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  1.17315498514759 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.03879628103677 bayes_pls_golite062009
  • hydrolase activity
    		•  1.03530755572346 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.950885142938701 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.949033593388493 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.918484127528225 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.917033090233205 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.915324862636953 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.836987306348926 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.833439952483443 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.833225286154786 bayes_pls_golite062009
  • nucleotide binding
    		•  0.826434767038468 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  0.442220326523999 bayes_pls_golite062009
  • ATP binding
    		•  0.304960869395329 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.276351989242018 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.265030176892253 bayes_pls_golite062009
  • catalytic activity
    		•  0.234613562021476 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.203102676509268 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.147644650870465 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  0.135455889967401 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle