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Protein Overview: SLC26A5

General Information:
Name(s) found: SLC26A5 [HGNC (HUGO)]
Description(s) found:
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  • gi|39752683|ref|NP_945350.1| prestin isoform a [Homo sapiens] [NCBI NR]
  • gi|30348882|gb|AAP31417.1| prestin [Homo sapiens] [NCBI NR]
  • gi|20139418|sp|P58743.1|S26A5_HUMAN RecName: Full=Prestin; AltName: Full=Solute carrier family 26 member 5 [NCBI NR]
  • gi|119603741|gb|EAW83335.1| solute carrier family 26, member 5 (prestin), isoform CRA_b [Homo sapiens] [NCBI NR]
  • solute carrier family 26, member 5 (prestin) [HGNC (HUGO)]
  • Prestin OS=Homo sapiens GN=SLC26A5 PE=2 SV=1 [Swiss-Prot]
  • (P58743) Prestin [Swiss-Prot]
  • Prestin [hmr_yeast5_DM3-1_pombe.fasta]
  • prestin isoform a; solute carrier family 26, member 5 [HMR_022704.fasta]
  • prestin isoform a [Homo sapiens]gi|30348882|gb|AAP31417.1| prestin [Homo sapiens]gi|20139418|sp|P58743|PRES_HUMAN Prestin [nrdb_11152004_Chlamydomonas]
  • Prestin (Solute carrier family 26 member 5) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Prestin [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • prestin isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • prestin isoform a; solute carrier family 26, member 5 [Homo sapiens] [HumanGallus06162005.fasta]
  • prestin (motor protein); solute carrier family 26, member 5 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • solute carrier family 26, member 5 (prestin), isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • prestin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Prestin [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SLC26A5 Isoform 1 of Prestin [human-ipi-250309-contam.fasta]
  • IPI:IPI00749380.1|SWISS-PROT:P58743-1|ENSEMBL:ENSP00000304783|REFSEQ:NP_945350|VEGA:OTTHUMP00000195085 Tax_Id=9606 Gene_Symbol=SLC26A5 Isoform 1 of Prestin [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • P58743;Q86UF8;Q86UF9;Q86UG0; RecName: Full=Prestin; AltName: Full=Solute carrier family 26 member 5; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Prestin OS=Homo sapiens GN=SLC26A5 [011711_HMR.fasta]
  • GeneSymbol=SLC26A5 Synonyms=DFNB61|MGC118886|MGC118887|MGC118888|MGC118889|PRES prestin isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Prestin GN=SLC26A5 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 744 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDHAEENEIL AATQRYYVER PIFSHPVLQE RLHTKDKVPD SIADKLKQAF TCTPKKIRNI  60
   61 IYMFLPITKW LPAYKFKEYV LGDLVSGIST GVLQLPQGLA FAMLAAVPPI FGLYSSFYPV 120
  121 IMYCFLGTSR HISIGPFAVI SLMIGGVAVR LVPDDIVIPG GVNATNGTEA RDALRVKVAM 180
  181 SVTLLSGIIQ FCLGVCRFGF VAIYLTEPLV RGFTTAAAVH VFTSMLKYLF GVKTKRYSGI 240
  241 FSVVYSTVAV LQNVKNLNVC SLGVGLMVFG LLLGGKEFNE RFKEKLPAPI PLEFFAVVMG 300
  301 TGISAGFNLK ESYNVDVVGT LPLGLLPPAN PDTSLFHLVY VDAIAIAIVG FSVTISMAKT 360
  361 LANKHGYQVD GNQELIALGL CNSIGSLFQT FSISCSLSRS LVQEGTGGKT QLAGCLASLM 420
  421 ILLVILATGF LFESLPQAVL SAIVIVNLKG MFMQFSDLPF FWRTSKIELT IWLTTFVSSL 480
  481 FLGLDYGLIT AVIIALLTVI YRTQSPSYKV LGKLPETDVY IDIDAYEEVK EIPGIKIFQI 540
  541 NAPIYYANSD LYSNALKRKT GVNPAVIMGA RRKAMRKYAK EVGNANMANA TVVKADAEVD 600
  601 GEDATKPEEE DGEVKYPPIV IKSTFPEEMQ RFMPPGDNVH TVILDFTQVN FIDSVGVKTL 660
  661 AGIVKEYGDV GIYVYLAGCS AQVVNDLTRN RFFENPALWE LLFHSIHDAV LGSQLREALA 720
  721 EQEASAPPSQ EDLEPNATPA TPEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] MSA 9.974989 View MSA. No confident structure predictions are available.
    2 View Details [257..504] MSA 4.984995 View MSA. No confident structure predictions are available.
    3 View Details [505..601] FFAS03 1.2 Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I
    4 View Details [602..744] PSI-BLAST 8.39794 Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.14643407404573 bayes_pls_golite062009
  • protein binding
    		•  1.48694301635456 bayes_pls_golite062009
    4
    Term Confidence Notes
  • binding
    		•  2.23164933258149 bayes_pls_golite062009
  • protein binding
    		•  1.6097880273634 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle