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Protein Overview: LMNB1

General Information:
Name(s) found: LMNB1 [HGNC (HUGO)]
Description(s) found:
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  • gi|74354337|gb|AAI03724.1| Lamin B1 [Homo sapiens] [NCBI NR]
  • gi|576840|gb|AAC37575.1| lamin B1 [Homo sapiens] [NCBI NR]
  • gi|5031877|ref|NP_005564.1| lamin B1 [Homo sapiens] [NCBI NR]
  • gi|307106|gb|AAA36162.1| lamin B [NCBI NR]
  • pir||VEHULB lamin B1 - human [NCBI NR]
  • gi|189069155|dbj|BAG35493.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|125953|sp|P20700.2|LMNB1_HUMAN RecName: Full=Lamin-B1 [NCBI NR]
  • gi|119569231|gb|EAW48846.1| lamin B1, isoform CRA_b [Homo sapiens] [NCBI NR]
  • lamin B1 [HGNC (HUGO)]
  • Lamin-B1 OS=Homo sapiens GN=LMNB1 PE=1 SV=2 [Swiss-Prot]
  • lamin B1 [Homo sapiens]gi|576840|gb|AAC37575.1| lamin B1 [Homo sapiens]gi|2144817|pir||VEHULB lamin B1 - humangi|125953|sp|P20700|LAM1_HUMAN Lamin B1gi|307106|gb|AAA36162.1| lamin B [nrdb_11152004_Chlamydomonas]
  • Lamin B1 [Yateslab_human_na_07-28-2006_reversed.fasta]
  • (NM_005573) lamin B1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • lamin B1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Lamin-B1 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • lamin B1, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Lamin B1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • lamin B [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 LAMIN B1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=LMNB1 Lamin-B1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00217975.4|SWISS-PROT:P20700|TREMBL:B2R6J6;B4DZT3|ENSEMBL:ENSP00000261366|REFSEQ:NP_005564|H-INV:HIT000195594|VEGA:OTTHUMP00000159218 Tax_Id=9606 Gene_Symbol=LMNB1 Lamin-B1 [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Lamin-B1 [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=LMNB1 Lamin-B1 ENSG00000113368 IPI00217975 IPI00790831 [drosphohumanreversed.fasta]
  • lamin-B1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P20700;B2R6J6;Q3SYN7;Q96EI6; RecName: Full=Lamin-B1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Lamin-B1 OS=Homo sapiens GN=LMNB1 [011711_HMR.fasta]
  • IPI:IPI00217975.4|SWISS-PROT:P20700|TREMBL:B4DZT3|ENSEMBL:ENSP00000261366|REFSEQ:NP_005564|H-INV:HIT000195594|VEGA:OTTHUMP00000159218 Tax_Id=9606 Gene_Symbol=LMNB1 Lamin-B1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=LMNB1 Synonyms=ADLD|LMN|LMN2|LMNB|MGC111419 lamin-B1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Lamin-B1 GN=LMNB1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 586 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATATPVPPR MGSRAGGPTT PLSPTRLSRL QEKEELRELN DRLAVYIDKV RSLETENSAL  60
   61 QLQVTEREEV RGRELTGLKA LYETELADAR RALDDTARER AKLQIELGKC KAEHDQLLLN 120
  121 YAKKESDLNG AQIKLREYEA ALNSKDAALA TALGDKKSLE GDLEDLKDQI AQLEASLAAA 180
  181 KKQLADETLL KVDLENRCQS LTEDLEFRKS MYEEEINETR RKHETRLVEV DSGRQIEYEY 240
  241 KLAQALHEMR EQHDAQVRLY KEELEQTYHA KLENARLSSE MNTSTVNSAR EELMESRMRI 300
  301 ESLSSQLSNL QKESRACLER IQELEDLLAK EKDNSRRMLT DKEREMAEIR DQMQQQLNDY 360
  361 EQLLDVKLAL DMEISAYRKL LEGEEERLKL SPSPSSRVTV SRASSSRSVR TTRGKRKRVD 420
  421 VEESEASSSV SISHSASATG NVCIEEIDVD GKFIRLKNTS EQDQPMGGWE MIRKIGDTSV 480
  481 SYKYTSRYVL KAGQTVTIWA ANAGVTASPP TDLIWKNQNS WGTGEDVKVI LKNSQGEEVA 540
  541 QRSTVFKTTI PEEEEEEEEA AGVVVEEELF HQQGTPRASN RSCAIM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..330] PSI-BLAST 13.522879 Heavy meromyosin subfragment
    2 View Details [331..394] FFAS03 3.2 Vimentin coil
    3 View Details [395..586] PSI-BLAST 20.69897 Lamin A/C globular tail domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • structural molecule activity
    		•  2.40638781086824 bayes_pls_golite062009
  • binding
    		•  2.29024114419453 bayes_pls_golite062009
  • protein binding
    		•  1.13460840277514 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle