Protein Overview: GPC6

General Information:
Name(s) found:	GPC6 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|9973298\|sp\|Q9Y625.1\|GPC6_HUMAN RecName: Full=Glypican-6; Contains: RecName: Full=Secreted glypican-6; Flags: Precursor [NCBI NR] gi\|76825240\|gb\|AAI06948.1\| Glypican 6 [Homo sapiens] [NCBI NR] gi\|5911318\|gb\|AAD55749.1\|AF105267_1 glypican-6 [Homo sapiens] [NCBI NR] gi\|55958500\|emb\|CAC21820.2\| glypican 6 [Homo sapiens] [NCBI NR] gi\|55957962\|emb\|CAC40695.2\| glypican 6 [Homo sapiens] [NCBI NR] gi\|55957903\|emb\|CAI15668.1\| glypican 6 [Homo sapiens] [NCBI NR] gi\|55661838\|emb\|CAH71332.1\| glypican 6 [Homo sapiens] [NCBI NR] gi\|55661805\|emb\|CAC39445.2\| glypican 6 [Homo sapiens] [NCBI NR] gi\|55661266\|emb\|CAH71606.1\| glypican 6 [Homo sapiens] [NCBI NR] gi\|5031719\|ref\|NP_005699.1\| glypican 6 precursor [Homo sapiens] [NCBI NR] gi\|4877643\|gb\|AAD31392.1\|AF111178_1 glypican-6 [Homo sapiens] [NCBI NR] gi\|37182048\|gb\|AAQ88827.1\| GPC6 [Homo sapiens] [NCBI NR] gi\|119629339\|gb\|EAX08934.1\| glypican 6, isoform CRA_d [Homo sapiens] [NCBI NR] glypican 6 [HGNC (HUGO)] Glypican-6 OS=Homo sapiens GN=GPC6 PE=1 SV=1 [Swiss-Prot] Glypican-6 precursor [hmr_yeast5_DM3-1_pombe.fasta] glypican 6 precursor [HMR_022704.fasta] GPC6 [Homo sapiens]gi\|5031719\|ref\|NP_005699.1\| glypican 6 precursor [Homo sapiens]gi\|55661838\|emb\|CAH71332.1\| OTTHUMP00000040768 [Homo sapiens]gi\|55661805\|emb\|CAC39445.2\| glypican 6 [Homo sapiens]gi\|55661266\|emb\|CAH71606.1\| OTTHUMP00000040768 [Homo sa [nrdb_11152004_Chlamydomonas] Tax_Id=9606 Glypican-6 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_005708) glypican 6 precursor [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] glypican 6 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Glypican-6 precursor [Contains: Secreted glypican-6] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] glypican 6 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] glypican 6, isoform CRA_d [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Glypican 6 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] GPC6 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] glypican-6 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 GLYPICAN-6 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=GPC6 Glypican-6 [human-ipi-250309-contam.fasta] IPI:IPI00001755.1\|SWISS-PROT:Q9Y625\|TREMBL:A8K279\|ENSEMBL:ENSP00000366246\|REFSEQ:NP_005699\|H-INV:HIT000069472\|VEGA:OTTHUMP00000018552 Tax_Id=9606 Gene_Symbol=GPC6 Glypican-6 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=GPC6 Glypican-6 precursor ENSG00000183098 IPI00001755 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=GPC6 Glypican-6 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] glypican-6 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Glypican-6 OS=Homo sapiens GN=GPC6 PE=2 SV=1 [UniProtHuman070710.fasta] Q9Y625;Q96SG5;Q96SG8;Q9H1P4; RecName: Full=Glypican-6; Contains: RecName: Full=Secreted glypican-6; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Glypican-6 OS=Homo sapiens GN=GPC6 [011711_HMR.fasta] GeneSymbol=GPC6 Synonyms=MGC126288\|OMIMD1 glypican-6 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00001755.1\|SWISS-PROT:Q9Y625\|ENSEMBL:ENSP00000366246\|REFSEQ:NP_005699\|H-INV:HIT000069472\|VEGA:OTTHUMP00000018552 Tax_Id=9606 Gene_Symbol=GPC6 Glypican-6 [ipi.HUMAN.20110912.fasta] Glypican-6 GN=GPC6 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	555 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSWIGAVIL PLLGLLLSLP AGADVKARSC GEVRQAYGAK GFSLADIPYQ EIAGEHLRIC  60
   61 PQEYTCCTTE MEDKLSQQSK LEFENLVEET SHFVRTTFVS RHKKFDEFFR ELLENAEKSL 120
  121 NDMFVRTYGM LYMQNSEVFQ DLFTELKRYY TGGNVNLEEM LNDFWARLLE RMFQLINPQY 180
  181 HFSEDYLECV SKYTDQLKPF GDVPRKLKIQ VTRAFIAART FVQGLTVGRE VANRVSKVSP 240
  241 TPGCIRALMK MLYCPYCRGL PTVRPCNNYC LNVMKGCLAN QADLDTEWNL FIDAMLLVAE 300
  301 RLEGPFNIES VMDPIDVKIS EAIMNMQENS MQVSAKVFQG CGQPKPAPAL RSARSAPENF 360
  361 NTRFRPYNPE ERPTTAAGTS LDRLVTDIKE KLKLSKKVWS ALPYTICKDE SVTAGTSNEE 420
  421 ECWNGHSKAR YLPEIMNDGL TNQINNPEVD VDITRPDTFI RQQIMALRVM TNKLKNAYNG 480
  481 NDVNFQDTSD ESSGSGSGSG CMDDVCPTEF EFVTTEAPAV DPDRREVDSS AAQRGHSLLS 540
  541 WSLTCIVLAL QRLCR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..106]	MSA	1.022986	View MSA. No confident structure predictions are available.
2	View Details	[107..237]	MSA	1.024944	View MSA. Confident ab initio structure predictions are available.
3	View Details	[238..306]	MSA	1.02798	View MSA. Confident ab initio structure predictions are available.
4	View Details	[307..377]	MSA	3.028986	View MSA. No confident structure predictions are available.
5	View Details	[378..555]	MSA	1.026947	View MSA. No confident structure predictions are available.

Protein Overview: GPC6

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: