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Protein Overview: TNFSF10

General Information:
Name(s) found: TNFSF10 [HGNC (HUGO)]
Description(s) found:
Found 40 descriptions.
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  • tumor necrosis factor (ligand) superfamily, member 10 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 281 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMMEVQGGP SLGQTCVLIV IFTVLLQSLC VAVTYVYFTN ELKQMQDKYS KSGIACFLKE  60
   61 DDSYWDPNDE ESMNSPCWQV KWQLRQLVRK MILRTSEETI STVQEKQQNI SPLVRERGPQ 120
  121 RVAAHITGTR GRSNTLSSPN SKNEKALGRK INSWESSRSG HSFLSNLHLR NGELVIHEKG 180
  181 FYYIYSQTYF RFQEEIKENT KNDKQMVQYI YKYTSYPDPI LLMKSARNSC WSKDAEYGLY 240
  241 SIYQGGIFEL KENDRIFVSV TNEHLIDMDH EASFFGAFLV G

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] MSA 3.05199 View MSA. No confident structure predictions are available.
    2 View Details [93..281] PSI-BLAST 60.69897 Apoptosis-2 ligand, apo2l/TRAIL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • CD40 receptor binding
    		•  3.4607762965927 bayes_pls_golite062009
  • receptor binding
    		•  3.37824597039547 bayes_pls_golite062009
  • tumor necrosis factor receptor superfamily binding
    		•  3.27382150819697 bayes_pls_golite062009
  • protein binding
    		•  2.25413201891408 bayes_pls_golite062009
  • binding
    		•  1.55055236820725 bayes_pls_golite062009
  • cytokine activity
    		•  1.44696622202601 bayes_pls_golite062009
  • cell surface binding
    		•  1.12145675554147 bayes_pls_golite062009
  • tumor necrosis factor receptor binding
    		•  0.83659914028185 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  0.3981620493951 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle