Protein Overview: NAC1_RAT

General Information:
Name(s) found:	NAC1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|78214331\|ref\|NP_062141.2\| solute carrier family 8, member 1 [Rattus norvegicus] [NCBI NR] gi\|1346652\|sp\|Q01728.3\|NAC1_RAT RecName: Full=Sodium/calcium exchanger 1; AltName: Full=Na(+)/Ca(2+)-exchange protein 1; Flags: Precursor [NCBI NR] Sodium/calcium exchanger 1 OS=Rattus norvegicus GN=Slc8a1 PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):6-4677765 Splice isoform 1 of Q01728 [hmr_yeast5_DM3-1_pombe.fasta] Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Sodium/calcium exchanger 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] solute carrier family 8, member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF SODIUM/CALCIUM EXCHANGER 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Slc8a1 Isoform 1 of Sodium/calcium exchanger 1 [rat-ipi-250309-contam.fasta] Isoform 1 of Sodium/calcium exchanger 1 OS=Rattus norvegicus GN=Slc8a1 [011711_HMR.fasta] Sodium/calcium exchanger 1 OS=Rattus norvegicus GN=Slc8a1 PE=2 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta] Isoform of Q01728, Sodium/calcium exchanger 1 OS=Rattus norvegicus GN=Slc8a1 PE=4 SV=2 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	971 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IEA] T-tubule [UNKNOWN][IDA] caveola [IPI] sarcolemma [UNKNOWN][IDA] mitochondrion [IDA] dendritic spine [IDA] integral to membrane [IEA] cell projection [IDA] plasma membrane [UNKNOWN][IMP] microtubule [IDA]
Biological Process:	transmembrane transport [IEA] telencephalon development [IEP] cell communication [IEA] response to ATP [IDA] response to nutrient [IEP] response to hydrogen peroxide [IEP] response to stress [IEP] calcium ion transport into cytosol [IDA] cellular calcium ion homeostasis [IMP] elevation of cytosolic calcium ion concentration [IMP] regulation of the force of heart contraction [UNKNOWN][IEA] sodium ion transport [UNKNOWN][IDA] regulation of sodium ion transport [IMP] ion transport [IEA] response to glucose stimulus [IEP] response to hypoxia [IDA] response to drug [IEP] calcium ion transport [UNKNOWN][TAS] cellular response to cAMP [IDA] regulation of calcium ion transport [IMP]
Molecular Function:	heat shock protein binding [IEA] calmodulin binding [IEA] protein binding [UNKNOWN][IDA] antiporter activity [IEA] calcium:sodium antiporter activity [UNKNOWN][IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLSLPPNV SMGFRLVTLV ALLFTHVDHI TADTEAETGG NETTECTGSY YCKKGVILPI  60
   61 WEPQDPSFGD KIARATVYFV AMVYMFLGVS IIADRFMSSI EVITSQEKEI TIKKPNGETT 120
  121 KTTVRIWNET VSNLTLMALG SSAPEILLSV IEVCGHNFTA GDLGPSTIVG SAAFNMFIII 180
  181 ALCVYVVPDG ETRKIKHLRV FFVTAAWSIF AYTWLYIILS VSSPGVVEVW EGLLTFFFFP 240
  241 ICVVFAWVAD RRLLFYKYVY KRYRAGKQRG MIIEHEGDRP ASKTEIEMDG KVVNSHVDNF 300
  301 LDGALVLEVD ERDQDDEEAR REMARILKEL KQKHPDKEIE QLIELANYQV LSQQQKSRAF 360
  361 YRIQATRLMT GAGNILKRHA ADQARKAVSM HEVNMDVVEN DPVSKVFFEQ GTYQCLENCG 420
  421 TVALTIIRRG GDLTNTVFVD FRTEDGTANA GSDYEFTEGT VIFKPGETQK EIRVGIIDDD 480
  481 IFEEDENFLV HLSNVRVSSE VSEDGILDSN HVSAIACLGS PNTATITIFD DDHAGIFTFE 540
  541 EPVTHVSESI GIMEVKVLRT SGARGNVIIP YKTIEGTARG GGEDFEDTCG ELEFQNDEIV 600
  601 KTISVKVIDD EEYEKNKTFF IEIGEPRLVE MSEKKALLLN ELGGFTLTEG KKMYGQPVFR 660
  661 KVHARDHPIP STVISISEEY DDKQPLTSKE EEERRIAEMG RPILGEHTKL EVIIEESYEF 720
  721 KSTVDKLIKK TNLALVVGTN SWREQFIEAI TVSAGEDDDD DECGEEKLPS CFDYVMHFLT 780
  781 VFWKVLFAFV PPTEYWNGWA CFIVSILMIG LLTAFIGDLA SHFGCTIGLK DSVTAVVFVA 840
  841 LGTSVPDTFA SKVAATQDQY ADASIGNVTG SNAVNVFLGI GVAWSIAAIY HAANGEQFKV 900
  901 SPGTLAFSVT LFTIFAFINV GVLLYRRRPE IGGELGGPRT AKLLTSSLFV LLWLLYIFFS 960
  961 SLEAYCHIKG F

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NAC1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: