YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CG8494-PA

General Information:
Name(s) found: CG8494-PA / FBpp0086664 [FlyBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • This gene is referred to in FlyBase by the symbol Dmel\CG8494 (CG8494, FBgn0033916). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10127442..10131167. It has the cytological map location 50E4-50E5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ubiquitin thiolesterase activity. There is experimental evidence that it is involved in the biological process</span>: nervous system development. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 975 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nervous system development [IMP]
    ubiquitin-dependent protein catabolic process [IEA]
    Molecular Function: ubiquitin thiolesterase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSSNPNPH NPYVEHRNRT IHSSQGHTLA NGYAMGDPRS SRCHDKLFSG SLKSLARRED  60
   61 SNASDSEGTD TAKGSGTGLV GLQNIANTCY MNSALQALSN LPPMTHYFIN CSDLVEYIAE 120
  121 QSARRCKPGG LAKSYRRLMQ EIWQDVDDPK EFIAPRGILY GIRTVHPMFR GYQQHDTQEF 180
  181 LRCFMDQLHE ELTEQVSMLP QTQNQPQYQS LQQQQPSETD DENDDEAAPA SLSHASESEY 240
  241 DTCESSMSER SAEVLLKTEY FVTPCRTNGS NSGLPEGHSV QLQQAPLQHQ QKNASSAEQK 300
  301 PIEAARSIIS DVFDGKLLSS VQCLTCDRVS TREETFQDLS LPIPNRDFLN VLHQTHSLSV 360
  361 QSLNAAETSA RTNEGWLSWM WNMLRSWIYG PSVTLYDCMA SFFSADELKG DNMYSCERCN 420
  421 KLRTGIKYSR VLTLPEVLCI HLKRFRNDLS YSSKISSDVY FPLEGFDMRP YIHKDCKSEV 480
  481 AIYNLSSVIC HHGTVGGGHY TCFARNTLNG KWYEFDDQFV TEVSSELVQS CQAYVLFYHK 540
  541 HNPQMKLVRD EAMTLSTSHP LCDSDIQFYI TREWLSRLAT FSEPGPINNQ EMLCPHGGIL 600
  601 HSKADVISQI AVPISQPLWD YLYRTFGGGP AVNIIFECEI CKRAAETLSR RQQYELNEFT 660
  661 KYNGLQNEFD STAIYAIAMP WLRSWQQFSR GKTHKDPGPI TNEGIAAPTE NGSATVSCVR 720
  721 LGSDYAQLNA RLWRFLHNIY GGGPEIILRQ ALSDEDDAEE IEIIDQDDEC DDDEDQDLEG 780
  781 EGEDEEIAAA SYQHNHSDTE SNLGIRNTPS PSPSTSPSPS LTGTRQPMET ESDLRPSSSK 840
  841 SKRSRSKMKV SALRLNMRNR GKRNRSAFKQ YAEMFGAKGN YNAHSNAEPV VSEKDEKDKD 900
  901 NDRTVAFPSE YSLPISIPFQ SDNFQVNGVH EKSRDKGKLR NSSKSGSTAA TKENVTLQKF 960
  961 VTLREANGPS DETDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..242] PSI-BLAST 13.0 Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution
    2 View Details [243..552] PSI-BLAST 37.30103 No description for 2gfoA was found.
    3 View Details [553..635] FFAS03 4.88 Solution structure of the DUSP domain of hUSP15
    4 View Details [636..779] PSI-BLAST 24.221849 Solution structure of the DUSP domain of hUSP15
    5 View Details [780..975] MSA 1.047973 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.15365778232348 bayes_pls_golite062009
  • protein binding
    		•  1.01235094804751 bayes_pls_golite062009
    4
    Term Confidence Notes
  • binding
    		•  1.25618438147954 bayes_pls_golite062009
  • protein binding
    		•  1.14865467626428 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle