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Protein Overview: Atg7-PB

General Information:
Name(s) found: Atg7-PB / FBpp0085890 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Autophagy-specific gene 7 is referred to in FlyBase by the symbol Dmel\Atg7 (CG5489, FBgn0034366). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14507961..14512553. It has the cytological map location 55E2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding; catalytic activity. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; macroautophagy; autophagy; larval midgut cell programmed cell death. 9 alleles are reported. The phenotype of these alleles is annotated with: adult brain. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 510 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: larval midgut cell programmed cell death [IMP]
    autophagy [IMP]
    determination of adult lifespan [IMP]
    macroautophagy [IMP]
    Molecular Function: catalytic activity [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTEKEIILQ FAPWESFVSP TFWHKLAELK LDHDRLSDSK RSITGHYTNR NASGCLLEVD  60
   61 YTAYNSPSFV GKPLKFLGLR HNQQMNIDDS LVWKVIQTEA CDLSQSENIK FVGWELNKNG 120
  121 KMGPRMVCMR DSMDPAKLAE NSVNLNLKLM KWRLVPDLNL EIISQTKCLL FGAGTLGCAV 180
  181 ARNLLSWGFK HITLLDSGKV GFSNPVRQNL YTHADAVAGN RMKATTAAQR LKEINPSAET 240
  241 AGYVLEIPMP GHTIGESLLA QTKEHLKVIE KLVQDHDVIF LLTDSRESRW LPTLLGAAKE 300
  301 KIVINAALGF DSYLVMRHGT TRKEAGDDGQ EIEGLKCING DQLGCYFCND VTAPGNSLKD 360
  361 RTLDQQCTVT RPGVSNIAAS YAVELLVALL QHPRKELAPA YYAQSGRGRS EETEEKVPEG 420
  421 LLGILPHSIR GMLCNYENIL PATQKFAQCI ACSAAVLNEY KKEGHAFLFK TFETAKFLED 480
  481 LTGISEFKRL NSEIIDFDDE EFDMSDSDED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..125] MSA 3.159992 View MSA. No confident structure predictions are available.
    2 View Details [126..425] PSI-BLAST 60.522879 Molybdenum cofactor biosynthesis protein MoeB
    3 View Details [426..510] MSA 3.368997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  1.59245438598251 bayes_pls_golite062009
  • binding
    		•  0.09659262506609 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle