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Protein Overview: CG3376-PA

General Information:
Name(s) found: CG3376-PA / FBpp0072173 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG3376 (CG3376, FBgn0034997). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20145552..20152746. It has the cytological map location 60C4. Based on sequence similarity, it is predicted to have molecular function</span>: sphingomyelin phosphodiesterase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: sphingomyelin catabolic process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 735 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: sphingomyelin catabolic process [IEA]
    Molecular Function: sphingomyelin phosphodiesterase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQQQPPWPS PISSSSSNPR GKCWLILVLM AVLPLVADVG ALPFLFTHIK PQINWTQPEM  60
   61 ESWVIEEQPR SIEPHLEPVL HPNRTHRALS SDSTDAEFLQ RLVSIRHNQT ASSRMLWYDV 120
  121 AGGDGLVYPP FVDKALKLLN LKQVAFEIEN SVMSKVTCTA CRAGAGMLQH QIQSGKTDAE 180
  181 LIRMITDYCT NLNIQSARVC QGVAQLFGSE LIYVLKRVNL SPDELCSFVI GDGCADVYNP 240
  241 YHEWEVIFPP VPKPPRLPDL PIPMEAAPFF KVLHISDTHY DPHYAEGSNA DCNEPLCCRL 300
  301 SSGRPATPNA AAGKWGDYRK CDTPKRTVDH MLSHIAETHK DIDYILWTGD LPPHDVWNQT 360
  361 KEENLAIIKD TVKQMVEMFP GVPIFPALGN HESAPVNSFP PPYVNQVDIS ISWLYDELDI 420
  421 QWRRWLPQSV THTVRRGAFY SVLVRPGFRI ISLNMNYCNN KNWWLLLNST DPATELQWFI 480
  481 YELQSAEFSN EKVHVIGHIP PGHSDCLKVW SRNFYKIISR YESTVTAQFY GHTHYDEFEM 540
  541 FYDPHDLNHP NGIAYIGPSV SPYYDLNPGY RIYYVDGDHD ATTRLVIDHE SWIMNLKEAN 600
  601 LYGYPIWYKL YTARAAYNMK ALRPSDWNNL LNELTNNQEL FELYYKYYWK NSPARPTCDA 660
  661 ECKKRLICDC RSGRSHDRKH FCAEVESKID EESSKSWKSW FYKGLTNSAE DRTEEPAPTT 720
  721 DGYGPFDVVI VNVGG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] deduced N/A No confident structure predictions are available.
    2 View Details [120..219] PSI-BLAST 17.0 No description for 2dobA was found.
    3 View Details [220..634] PSI-BLAST 43.30103 Sweet potato purple acid phosphatase/phosphate complex
    4 View Details [635..735] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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