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Protein Overview: sle-PA

General Information:
Name(s) found: sle-PA / FBpp0081710 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene slender lobes is referred to in FlyBase by the symbol Dmel\sle (CG12819, FBgn0037810). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6158893..6163995. It has the cytological map location 86A8-86B1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: nucleolus organization. 6 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body; neuroblast; nucleolus; mushroom body beta-lobe; mushroom body alpha-lobe. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1420 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    spindle [IDA]
    nucleolus [IDA]
    Biological Process: nucleolus organization [IMP]
    brain development [NAS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVTRARTRR LSLLETDSRP STPQLDTVAE LGTASPRATR RTRLNSSTLD VRTPTRTRRA  60
   61 SLARGETPEP TTPSSVKRTA RTPAKNTRSV RQQLTLTEEP EENEVKQEKP SPSPSPVPKE 120
  121 GKGKAQRKPS VSPSPGRTLT PNQQSDEKRV TRSMSQTPPM PTRSSSNTPR DLNDSPKVEQ 180
  181 KAKPNIKTTP KVAVRLEKLS MDKFSGKKME KAKPLIVPDE LKDNGVVEEQ NKSITEAHSQ 240
  241 APETHESAQP DKDAGKQSFL KSFTTLSKIQ GSSKALHPDE SADTITKITP TSTSKKIEEN 300
  301 MDDVFETLRV ESPKVERKIE TLQKVHTVGT PEIKEKDEPV GVDNEIKTKT ETPQKIEPPI 360
  361 IESKVETQQL IDHPQIEKKR DTPQNVSTVD LMDTSPEKDE SMEDQEFLDA EDSIVQLEPQ 420
  421 TDEPVEKPKE LEFVDLDDDE PVFPSEAPKY VEDSKEVHPD DSMDDDKQNK IDVTEVIHLP 480
  481 SIRARAVRSP AVEQKKSVDF NNDTDDLEVE KKRFPKTPGR EKVPVCRILT PKPETPLKLA 540
  541 LQKGRNSSTP ILKDQERGLS NSTEELHPAP PQIDAIKPFD ELESKNAKDE MVEQSPMSKQ 600
  601 KAENKILARL ESFEEDVEDH GNEEENEEEH EEDKSISEFV DLEAEDAGKD YMSGDSMDSS 660
  661 LRREMEENEI PIDGESVGSK DTEESTPEES DGDDSFIVSD NEDEEDLGQL CYSSGEDEIE 720
  721 DAEESEQAER SSVKRRRIII ASPSDEEHDG KVQSNDDSSE NKTEKPKNQS NCSSNASKLS 780
  781 EAAQLLNVSE EKSSISETEL ERSRQVALNE LNKSERFNKT ETQLDISVME VDSSDHDEEE 840
  841 KTEKVGAKNN RSLYEIVDSD DGEEQDQDQS DADKPAESEN HSEIKKSTSF MDQMSGAKGN 900
  901 KSVYEIMDSY ETEDPKEAGK NEESDKDKPA ENGKSDKDKQ AETEMSDEDK PSEIKSPSTI 960
  961 KKSIISTADE EALLAELASS DLSHLEKMFN PLQKSRRQSL HVPSPELAAK NPKLRRRSER1020
 1021 VEVGNDFCPS QSFVDMVAEK KRQKNKRKRL SKSLSGAPED LEEMEIKHER KRLKSSHGAS1080
 1081 TDSMEEDNEN ETMTVAEEHH SDGEVSNGEV PIEEKPTTSS EKPSASELPE EEETVAVEEL1140
 1141 LMEKPKTCDS PRSEERPTEI VTSKPKGMAP VKVEKTAEYY LAYCHNLLEA ANEAKLKEKK1200
 1201 EHLASGAKQK KPKRIAAQAP SKLLGTIGSE SETNTAKSSK QPPALKKDVK RLQAARQAVS1260
 1261 HAVNLLAPPK ATEAEPRTLS RKLSPQPPVV DKKSAKQKKG KKKQKPQEAS PLKSSDEENH1320
 1321 GHRIRTNAGY VTVVDEPPTK VPKIELIKTS SGMVRVEPCT PKQKYFRELP PTPKMHGFRE1380
 1381 EPGPSGMSRK RAKHAAPKVE HNSAKQAALR FKEQIFARRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] FFAS03 1.12 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
    2 View Details [295..486] deduced N/A No confident structure predictions are available.
    3 View Details [487..593] deduced N/A No confident structure predictions are available.
    4 View Details [594..1065] FFAS03 1.71 30S subunit
    5 View Details [1066..1229] deduced N/A No confident structure predictions are available.
    6 View Details [1230..1420] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle