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Protein Overview: hex-1

General Information:
Name(s) found: hex-1 / CE07499 [WormBase]
Description(s) found:
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  • WBGene00020509 locus:hex-1 Beta-hexosaminidase A status:Confirmed UniProt:Q22492 protein_id:CCD68941.1 [WormBase]
  • pir||T29377 hypothetical protein T14F9.3 - Caenorhabditis elegans [NCBI NR]
  • gi|6919908|sp|Q22492.1|HEXA_CAEEL RecName: Full=Beta-hexosaminidase A; AltName: Full=N-acetyl-beta-glucosaminidase; AltName: Full=Beta-N-acetylhexosaminidase; Flags: Precursor [NCBI NR]
  • gi|17569815|ref|NP_508409.1| HEXosaminidase family member (hex-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|152942507|emb|CAO72174.1| hexosaminidase [Caenorhabditis elegans] [NCBI NR]
  • gi|1213554|gb|AAA91263.1| Hypothetical protein T14F9.3 [Caenorhabditis elegans] [NCBI NR]
  • Beta-hexosaminidase A OS=Caenorhabditis elegans GN=hex-1 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE07499 WBGene00020509 beta-hexosaminidase beta subunit status:Confirmed SW:Q22492 protein_id:AAA91263.1 [wormpep150.fasta]
  • 07499 WBGene00020509 beta-hexosaminidase beta subunit status:Confirmed SW:Q22492 protein_id:AAA91263.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • beta-hexosaminidase (64.4 kD) (XC843) [Caenorhabditis elegans]gi|1213554|gb|AAA91263.1| Hypothetical protein T14F9.3 [Caenorhabditis elegans]gi|7507830|pir||T29377 hypothetical protein T14F9.3 - Caenorhabditis elegansgi|6919908|sp|Q22492|HEXA_CAEEL Pro [nrdb_11152004_Chlamydomonas]
  • beta-hexosaminidase beta subunit status:Confirmed SW:Q22492 protein_id:AAA91263.1 [wormpep115.fasta.reversed]
  • CE07499 beta-hexosaminidase beta subunit status:Confirmed SW:Q22492 protein_id:AAA91263.1 [wormpep80.hongbin]
  • CE07499 WBGene00020509 locus:hex-1 beta-hexosaminidase beta subunit status:Confirmed UniProt:Q22492 protein_id:AAA91263.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE07499 WBGene00020509 locus:hex-1 beta-hexosaminidase beta subunit status:Confirmed UniProt:Q22492 protein_id:AAA91263.1| [wormORF-contam.fasta]
  • Hypothetical protein T14F9.3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable beta-hexosaminidase A precursor (N-acetyl-beta-glucosaminidase) (Beta-N-acetylhexosaminidase) [nr-271106-contam.fasta]
  • T14F9.3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE07499 WBGene00020509 locus:hex-1 beta-hexosaminidase beta subunit status:Confirmed SW:Q22492 protein_id:AAA91263.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE07499 WBGene00020509 locus:hex-1 beta-hexosaminidase beta subunit status:Confirmed UniProt:Q22492 protein_id:CCD68941.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE07499 WBGene00020509 locus:hex-1 status:Confirmed UniProt:Q22492 protein_id:CCD68941.1 Beta-hexosaminidase A [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 555 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: carbohydrate metabolic process [IEALink to PubMed article]
    Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds [IEALink to PubMed article]
    beta-N-acetylhexosaminidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLIPILIF ALITTAVTWF YGRDDPDRWS VGGVWPLPKK IVYGSKNRTI TYDKIGIDLG  60
   61 DKKDCDILLS MADNYMNKWL FPFPVEMKTG GTEDFIITVT VKDECPSGPP VHGASEEYLL 120
  121 RVSLTEAVIN AQTVWGALRA MESLSHLVFY DHKSQEYQIR TVEIFDKPRF PVRGIMIDSS 180
  181 RHFLSVNVIK RQLEIMSMNK LNVLHWHLVD SESFPYTSVK FPELHGVGAY SPRHVYSRED 240
  241 IADVIAFARL RGIRVIPEFD LPGHTSSWRG RKGFLTECFD EKGVETFLPN LVDPMNEANF 300
  301 DFISEFLEEV TETFPDQFLH LGGDEVSDYI VECWERNKKI RKFMEEKGFG NDTVLLENYF 360
  361 FEKLYKIVEN LKLKRKPIFW QEVFDNNIPD PNAVIHIWKG NTHEEIYEQV KNITSQNFPV 420
  421 IVSACWYLNY IKYGADWRDE IRGTAPSNSR YYYCDPTNFN GTVAQKELVW GGIAAIWGEL 480
  481 VDNTNIEARL WPRASAAAER LWSPAEKTQR AEDAWPRMHE LRCRLVSRGY RIQPNNNPDY 540
  541 CPFEFDEPPA TKTEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..555] PSI-BLAST 146.0 Human beta-Hexosaminidase B

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  6.26329339735894 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  5.92180849080637 bayes_pls_golite062009
  • galactosidase activity
    		•  5.29959220339307 bayes_pls_golite062009
  • alpha-galactosidase activity
    		•  4.85819791163713 bayes_pls_golite062009
  • hydrolase activity
    		•  3.5336140444552 bayes_pls_golite062009
  • hexosaminidase activity
    		•  3.21852337137039 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  2.69072465526737 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • glucosidase activity
    		•  1.85545420386612 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  1.00973231642658 bayes_pls_golite062009
  • signal transducer activity
    		•  0.934517587656668 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.934517587656668 bayes_pls_golite062009
  • transporter activity
    		•  0.882190348056302 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.696239852087965 bayes_pls_golite062009
  • binding
    		•  0.601963252939415 bayes_pls_golite062009
  • beta-glucuronidase activity
    		•  0.55376725638834 bayes_pls_golite062009
  • mannosidase activity
    		•  0.48536369022293 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.223550370855368 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  7.36798954279472E-5 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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