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Protein Overview: C78A9_ARATH

General Information:
Name(s) found: C78A9_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|6899886|emb|CAB71895.1| cytochrome p450 (CYP78A9) [Arabidopsis thaliana] [NCBI NR]
  • gi|6633989|dbj|BAA88569.1| cytochrome P450 [Arabidopsis thaliana] [NCBI NR]
  • gi|31711948|gb|AAP68330.1| At3g61880 [Arabidopsis thaliana] [NCBI NR]
  • gi|17065344|gb|AAL32826.1| cytochrome p450 (CYP78A9) [Arabidopsis thaliana] [NCBI NR]
  • gi|15228624|ref|NP_191747.1| CYP78A9 (CYTOCHROME P450 78A9); monooxygenase/ oxygen binding [Arabidopsis thaliana] [NCBI NR]
  • pir||T47980 cytochrome P450 CYP78A9 homolog F21F14.50 [similarity] - Arabidopsis thaliana [NCBI NR]
  • Cytochrome P450 78A9 OS=Arabidopsis thaliana GN=CYP78A9 PE=2 SV=1 [Swiss-Prot]
  • (Q9SLP1) Cytochrome p450 (CYP78A9) (At3g61880) [athaliana3702.FASTAC.txt]
  • At3g61880 [Arabidopsis thaliana]gi|6633989|dbj|BAA88569.1| cytochrome P450 [Arabidopsis thaliana]gi|6899886|emb|CAB71895.1| cytochrome p450 (CYP78A9) [Arabidopsis thaliana]gi|17065344|gb|AAL32826.1| cytochrome p450 (CYP78A9) [Arabidopsis thaliana]gi|1 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Cytochrome P450 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: CYP78A9 | CYP78A9 (CYTOCHROME P450 78A9); oxygen binding | chr3:22917089-22918865 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At3g61880 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • cytochrome p450 (CYP78A9) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • cytochrome P450 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • CYP78A9 (CYTOCHROME P450 78A9); oxygen binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: CYP78A9 | cytochrome p450 78a9 | chr3:22906114-22907890 REVERSE LENGTH=534 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • At3g61880 OS=Arabidopsis thaliana GN=CYP78A9 PE=2 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 534 amino acids

    Gene Ontology:
    Cellular Component: endomembrane system [IEA]
    Biological Process: fruit development [IMP]
    Molecular Function: oxygen binding [ISS]
    monooxygenase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKLDTSSL LLALLSKCSL LTQTNLALSL LVASLASLAL SLFFWSHPGG PAWGKYFLHR  60
   61 RRQTTVIPGP RGLPFVGSMS LMSNTLAHRC IAATAEKFRA ERLMAFSLGE TRVIVTCNPD 120
  121 VAKEILNSPV FADRPVKESA YSLMFNRAIG FAPYGVYWRT LRKIASNHLF SPKQIKRSET 180
  181 QRSVIANQIV KCLTKQSNTK GLCFARDLIK TASLNNMMCS VFGKEYELEE EHEEVSELRE 240
  241 LVEEGYDLLG TLNWTDHLPW LSEFDPQRIR SRCSNLVPKV NRFVNRIISD HREQTRDSPS 300
  301 DFVDVLLSLD GPDKLSDPDI IAVLWEMIFR GTDTVAVLIE WILARMVLHP DIQSTVHNEL 360
  361 DQIVGRSRAV EESDVVSLVY LTAVVKEVLR LHPPGPLLSW ARLAITDTII DGRRVPAGTT 420
  421 AMVNMWAIAH DPHVWENPLE FKPERFVAKE GEVEFSVLGS DLRLAPFGSG RRVCPGKNLG 480
  481 LTTVTFWTAT LLHEFEWLTP SDEKTVDLSE KLRLSCEMAN PLAAKLRPRR SFSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..534] PSI-BLAST 101.0 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • electron carrier activity
    		•  4.64931978461551 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  3.99744233006162 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  3.76307535769621 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • demethylase activity
    		•  3.40807632433846 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  3.16634614522939 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.94610675710811 bayes_pls_golite062009
  • oxygen binding
    		•  2.77495508953933 bayes_pls_golite062009
  • retinoic acid binding
    		•  2.70323898361882 bayes_pls_golite062009
  • retinoid binding
    		•  2.60220937953757 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • isoprenoid binding
    		•  2.47826119804163 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  2.36480328243514 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  2.15105968497418 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  2.0071742914584 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • corticosterone 18-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • steroid 11-beta-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  1.48500938886158 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.46109575978397 bayes_pls_golite062009
  • binding
    		•  1.2866152532988 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • protein binding
    		•  0.836411857417911 bayes_pls_golite062009
  • ecdysteroid 22-hydroxylase activity
    		•  0.7601272997427 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.203772707673481 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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