YRC Public Data Repository - Protein Structure Prediction

Protein:	SET5
Organism:	Saccharomyces cerevisiae
Length:	526 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SET5.

Description	E-value	Query Range	Subject Range
CG7759-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7759 (CG7759, FBgn0033633). It is a protein...	220.0	[0..56]	[516..169]
gi\|125810418\|ref... - GA20567-PA [Drosophila pseudoobscura], GA20567 [Drosophila pseudoobscura pseudoobscura] gi\|54636660, gi\|... - gi\|54636660\|gb\|EAL26063.1\| GA20567 [Drosophila pseudoobscura pseudoobscura], gi\|125810418\|ref\|XP_001...	209.0	[0..56]	[516..169]
gi\|21754614 - gi\|21754614\|dbj\|BAC04538.1\| unnamed protein product [Homo sapiens]	209.0	[0..92]	[507..216]
ASHH3_ARATH - Histone-lysine N-methyltransferase ASHH3 OS=Arabidopsis thaliana GN=ASHH3 PE=2 SV=2	206.0	[0..277]	[524..107]
SET5_CANGA - Potential protein lysine methyltransferase SET5 OS=Candida glabrata GN=SET5 PE=3 SV=1 SET5_CANGA - Potential protein lysine methyltransferase SET5 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JC...	204.0	[0..3]	[525..6]
gi\|114665632, gi... - gi\|114665634\|ref\|XP_001155346.1\| PREDICTED: SET and MYND domain containing 4 isoform 2 [Pan troglody...	203.0	[0..92]	[507..216]

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Predicted Domain #1

Region A:
Residues: [1-112]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLTIKIGTL NDSDQSAVHN GTENGSDFRK ITPTEEEICD DVVLLWKEEP GTEDATIQHL  60
   61 YDRITERNQS WKLSASRFRK ILNEHHLYDT DLETVSLYKD KIHFPKALDS DA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [113-433]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVEVKFIDDE HGRGLFAKRD FSKGQIILKE NKPIVYIPPL DKLFLISNGK ACARCGKALY  60
   61 DLTQHKIMVH YLDCEVCKAI WCSEKCKKAH ASLHELLYHS WRSNRIDILH AGNWKRFVNY 120
  121 CEKYCFTAAF SVGLIYGSML LDTTGEVKEQ WQKLASISQR ERIKLRDASG IGSTFSLLNG 180
  181 TTVHTEEESD NGTKKGVEKN IDDETVWEKC YELFCGAFPK ASEEIDFEKF LTMIGTFNIN 240
  241 QYNGQVYHWI SFINHDCEPN AYIEQVEEHE ELRLHARKPI KKGEQIRITY VNPLHGVRLR 300
  301 RRELRVNWGF LCQCDRCQNE L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.39794
Match:	1mvhA
Description:	SET domain of Clr4
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [434-526]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STFERVPNLE KKNADANLGV EKIDSNDSSE DGSKKSTGNR KSSMREAQPD LKEILKNGKE  60
   61 FELDIPETVD TQGNVRKTSV RFDSNVSVAV DER

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits