| Protein: | PBX1 |
| Organism: | Homo sapiens |
| Length: | 430 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PBX1.
| Description | E-value | Query Range |
Subject Range |
|
|
1.0E-66 | [1..430] | [1..430] |
|
|
1.0E-64 | [1..430] | [1..430] |
|
|
2.0E-63 | [1..430] | [1..422] |
|
|
1.0E-62 | [1..430] | [1..453] |
|
|
1.0E-60 | [1..430] | [1..428] |
|
|
1.0E-60 | [1..430] | [1..430] |
|
|
1.0E-57 | [1..430] | [1..434] |
|
|
2.0E-57 | [1..430] | [1..434] |
|
Region A: Residues: [1-83] |
1 11 21 31 41 51
| | | | | |
1 MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI MTITDQSLDE 60
61 AQARKHALNC HRMKPALFNV LCE
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [84-236] |
1 11 21 31 41 51
| | | | | |
1 IKEKTVLSIR GAQEEEPTDP QLMRLDNMLL AEGVAGPEKG GGSAAAAAAA AASGGAGSDN 60
61 SVEHSDYRAK LSQIRQIYHT ELEKYEQACN EFTTHVMNLL REQSRTRPIS PKEIERMVSI 120
121 IHRKFSSIQM QLKQSTCEAV MILRSRFLDA RRK
|
| Detection Method: | |
| Confidence: | 0.981 |
| Match: | 2h8rA |
| Description: | No description for 2h8rA was found. |
|
Region A: Residues: [237-332] |
1 11 21 31 41 51
| | | | | |
1 RRNFNKQATE ILNEYFYSHL SNPYPSEEAK EELAKKCGIT VSQVSNWFGN KRIRYKKNIG 60
61 KFQEEANIYA AKTAVTATNV SAHGSQANSP STPNSA
|
| Detection Method: | |
| Confidence: | 17.30103 |
| Match: | 1b72B |
| Description: | pbx1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.5139760613123 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| transcription activator activity | 3.10621734076555 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| protein binding | 1.88087411289001 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.62096064323298 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [333-430] |
1 11 21 31 41 51
| | | | | |
1 GSSSSFNMSN SGDLFMSVQS LNGDSYQGAQ VGANVQSQVD TLRHVISQTG GYSDGLAASQ 60
61 MYSPQGISAN GGWQDATTPS SVTSPTEGPG SVHSDTSN
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
